The 'Love Island' star has been embroiled in a war of words with the YouTuber on social media and thinks it will be a "comfortable night's work" if a fight is arranged.
Fury told talkSPORT: "If you're asking me would I like to take the fight? Would it be a comfortable night's work and would it be beneficial to me? Yeah, it ticks every box so why not. I'm going to continue with my career so if he wants to fight, which is highly unlikely as he's got no balls, I'll happily take that fight."
Paul - who has won all three fights in his career but is yet to face an actual boxer - criticised Fury for taking on weak opponents but the fighter suggested that he will not be altering his career path for the benefit of the social media star.
Fury said: "I'm not going to take any detours for Jake Paul in the way I do things. I'm going to keep doing me, training the way I'm training and the fighters I fight to get that experience. If Jake Paul comes into it, that's fine, I'll happily fight with him very comfortably. It's a good thing as I don't have to change what I'm going to do.
"If he wants to fight, it's here because it's a comfortable night's work and very beneficial. I'm not going to start changing my career for Jake Paul."