The 40-year-old head coach has insisted it was "not our day" after the Red Devils were held to a 1-1 draw against the side bottom of the Premier League, who had lost their previous 11 games and now have just three points on the board.
On the topic of his team conceding just before half time, Amorim told BBC's Match of the Day: "We need to work on that because it's not the first time. The fluidity of the game was not there. We tried.
"We tried to overload one side, but in the Premier League you need one v one, and you need that, and we didn't have it today.
"We don't have the guys that play outside - we tried to overload the middle, but today was not our day.
"Even against Everton, it was three points lost, West Ham was two points lost. Always frustrating. Football is like that. If you focus on the performance, we struggled today."
He described the game a "strange" following a big 1-0 win over Newcastle United on Boxing Day (26.12.25), which meant a win against Wolves would have put United in fourth place in the Premier League.
He added: "Strange game. We knew it would be a different game to Newcastle. We needed more imagination today to create chances.
"We struggled in the first half trying to steal the ball.
"They put a lot of men in the midfield. We tried, but the quality was not there. We need to recover to the next one."
United are missing some key players - Mason Mount, Kobbie Mainoo and Bruno Fernandes were unavailable due to injury, while Bryan Mbeumo, Amad Diallo and Noussair Mazraoui are away at the Africa Cup of Nations.
However, Amorim refused to blame the poor result on the absentees.
He said: "Not using anything as an excuse. We tried to put two strikers in and then conceded from a set piece. Today was not our day."