The season-opening Australian Grand Prix this weekend will herald a new dawn for the sport - with an increased emphasis on energy management instead of driving flat out - and Domenicali was disappointed to hear former world champion Max Verstappen and Lewis Hamilton talk disparagingly about the new rules during pre-season testing.
In an interview with Sky Sports, the F1 chief said: "I think it's wrong, in general terms, to talk bad about an incredible world that is allowing all of us to grow. And that's the only thing that I would say is not right.
"But, you know, I always listen [with] prudency. There is an evolution of driving, it means that the best driver will be able to be the fastest."
Domenicali is looking forward to the talk stopping when the new campaign gets underway in Melbourne on Sunday (08.03.26).
The former Ferrari team principal said: "I'm feeling good. I'm feeling good because we have the duty of bringing positivity in this moment of what we live in. I feel good because there is a lot of attention about what is happening on the track.
"I feel good because we are in Melbourne with an incredible crowd, incredible, passionate people. We have seen another step of being very attractive for the younger generation, and that's thanks to what we are trying to do together.
"That's why I do believe that the strategy we have taken is the right one. To keep really hammering down, knowing that we can sit and be focused on delivering something more for our fans."
The new cars appear to be much slower than last year's models but Domenicali expects them to gain speed over time and has also promised to address any issues caused by the new regulations.
He said: "I think that the possibility to develop this car, both from the engineering point of view and also from the driver's point of view, will enable us to see very, very soon a car that will be faster.
"The world of engineers behind F1 is incredible. The approach that we have discussed already in the last F1 Commission with the FIA, with the teams, very openly. If we see something that needs to be addressed, we're going to address it in the right way.
"But I think that now we are on a course where everyone realises that if there is something clear that has to be done to improve [F1], why not? Let's do it."