The English golfer claimed his lone major at the US Open back in 2013 and has been unable to add to his tally despite several near-misses, although he is satisfied with what he has achieved in the game regardless.
Speaking ahead of this year's US Open at Shinnecock Hills, Rose said: "Yeah, multiple major champion is better than a major champion. Multiple of anything that I’ve achieved in my career, I would love more of what I’ve done. I’m very grateful for the things I’ve achieved. I’d love more of it all, but yeah, I don’t think it changes my career."
The 2016 Olympic gold medallist explained that he doesn't feel any additional pressure when taking to the course at major championships.
Rose said: "It will change my career in the sense that I prove to myself over, again, another big gap that it would be like winning — the challenge of winning another one would be like winning for the first time, I think. Just having pushed myself to sort of find that level.
"You need to push yourself to find that level in the first instance, and I think where I’m at in my career now, pushing myself to find that final kind of level again to win another one would be a lot of self-satisfaction. I don’t think it necessarily, massively changes my standing in the game."
Rose, 45, will become the oldest US Open champion should he triumph this week and explained how he has made "sacrifices" to remain competitive in the biggest events as he gets older.
The world number seven said: "I try to make sure I’m getting my recovery right and trying to make sure I’m getting my preparation cycles right to play well in the big events. I potentially sacrifice a few things along the way to try to make that happen. Obviously that’s a very hard thing to do, is to kind of peak on demand, but you’ve got to give it a go, right?"