The two boxers fought twice in the 1990s, with Holyfield upsetting the odds to win in 1996 before the infamous rematch the following year in which Tyson was disqualified for biting his opponent's ear.
Holyfield admits that he is keen to face Tyson once again after his rival returned to the ring last year in an exhibition fight with Roy Jones Jr.
He told The Sun newspaper: "The thing is that if it's meant to be it will happen, either way, it is what it is.
"What I can tell you is that my team is talking to Mike's management, so I'm waiting for a decision. They are communicating right now. The thing is I'm still training for this, I know it will be some day this deal will happen and I'm ready for him. I'm doing OK."
The former heavyweight champion believes the possible clash will be "the biggest fight there is".
Holyfield said: "My views are you always help people. I try to pass on the goodness that was passed onto me. Where an opportunity is available, I like to make the best out of what I have. I believe if I fought Mike the fight will generate $200 million. It will be the biggest fight there is. That's the honest truth. I think Mike has my message already. It's a decision he has to make now and we both have to be in an agreement.
"I'm not going to tell anybody what I'm going to do – my strategy I'm planning on using against Mike – I don't want anyone to know. I'm happy if Mike fights me."