The heavyweight world champions will meet in a blockbuster clash in Saudi Arabia on February 17 and Tyson is convinced that The Gypsy King will bounce back from his mediocre performance against Francis Ngannou to become undisputed heavyweight world champion.
Iron Mike - who worked with Ngannou in the lead-up to last month's clash with Fury - told Fight Hub TV: "Hey, we should [not focus on what Fury did against Ngannou], but you have to understand he is still the champion. He made that night a great night. He gave Francis the opportunity and that was just a bad night at the office for him. We all have bad nights, and listen, that was his bad night.
"I look forward to that fight [between Fury and Usyk]. That is going to be an interesting fight. I’m going towards Tyson Fury because I think he’s just going to overpower him. He’s going to catch up with him and overpower him.
"I got to go with Fury. I think he’s the best fighter in the world, especially in the heavyweight division. Great fighters lose, great fighters look bad, [but] that doesn’t stop them from being great fighters."
Tyson also heaped praise on "once in a lifetime" Fury for being so successful in the ring despite his giant stature.
The former world champion said of the British fighter: "He is rare, he is just rare. He’s once in a lifetime.
"To be that successful [at that size], there have always been big guys that maybe look obese or overweight, but they have never been that successful."