The Chinese tech giants - who are the world's largest maker of telecoms equipment - were recently added to a list of companies that US firms cannot trade with unless they have a license, amid the fears of national security concerns.
But Huawei have repeatedly denied allegations that the use of their products presents security risks, and says it is independent from the Chinese government.
Song Liuping, the firm's top legal officer, said at a press conference: "Politicians in the US are using the strength of an entire nation to come after a private company.
"This decision threatens to harm our customers in over 170 countries, including more than three billion consumers who use Huawei products and services around the world.
"By preventing American companies from doing business with Huawei, the government will directly harm more than 1,200 US companies. This will affect tens of thousands of American jobs."
Liuping also outlined the steps Huawei have taken in relation to a lawsuit the company filed against the US government in March, which relates to restrictions that prevent US federal agencies from using Huawei products.
Huawei said it has filed a motion for a "summary judgement", asking US courts to speed up the process to "halt illegal action against the company".
Liuping added at the Shenzhen conference: "The US government has provided no evidence to show that Huawei is a security threat. There is no gun, no smoke. Only speculation."
A hearing on the motion is due to take place on September 19.