The space agency has confirmed the exciting news this week, and the ambitious plan will see a rotorcraft vehicle land on the icy natural satellite.
It's said the flying craft is designed to land in a number of locations - from dunes to the floor of an impact crater - to carry out science mission in the hunt for the "building blocks of life".
NASA's Thoas Zurbucen said: "Dragonfly will visit a world filled with a wide variety of organic compounds, which are the building blocks of life and could teach us about the origin of life itself."
Titan itself - the second largest moon in the solar system - is home to huge methane lakes and mysterious vanishing islands.
With dozens of planned landing sites, it's expected Dragonfly will aim for an initial mission spanning 2.7 years.
Engineers are hoping it can cover more than 108 miles of the moon's surface, which would nearly double the distance all Mars rovers - combined - have traveled to date.
NASA added: "Dragonfly marks the first time NASA will fly a multirotor vehicle for science on another planet; it has eight rotors and flies like a large drone."